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Dr. Louis-Félix Nothias
CNRS University Côte d’Azur, France

Dr. Louis-Félix Nothias is a CNRS junior group leader at the University Côte d’Azur and the Interdisciplinary Institute for Artificial Intelligence (3iA) Côte d’Azur in France. In July 2023, he founded the Holobiomics Lab, which develops experimental and computational methods for studying host/microbial metabolism in holobionts and their microbiomes. The lab pioneers advanced, AI-driven, mass spectrometry-based metabolomics techniques within multi-omics studies, and it designs AI systems to assist with omics data analysis and interrogation. Before founding the Holobiomics Lab, Dr. Nothias was a postdoctoral researcher at the University of California San Diego (2016–2021) under Prof. Pieter Dorrestein, where he contributed to the GNPS ecosystem. Subsequently, he served as a research associate at the University of Geneva with Prof. Jean-Luc Wolfender (2021–2023). Over the course of his career, Dr. Nothias has contributed to both experimental and computational methods for MS-based metabolomics annotation—including collaborations with the SIRIUS team (Boecker lab, see CASMI 2022)—and has contributed to integrative multi-omics approaches for the study of microbially-related metabolites in diverse ecosystems, notably through the collaborative Earth Microbiome Project.

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